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To avoid false-favourable benefits, the 99th percentile needs to be utilised as the Reduce-off benefit for diagnosing acute myocardial infarction. The usage of two Minimize-off values51,52 — 1 to define infarction in addition to a second designation for unstable angina with some diploma of myocardial necrosis — has been suggested.51,52 The ESC/
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